Selected Publications
(* Corresponding author,# co-first author)
1.X. Lan* and J. K. Pritchard*, “Coregulation of tandem duplicate genes slows evolution of subfunctionalization in mammals.,” Science, vol. 352, no. 6288, pp. 1009–1013, 2016.
2.B. Liu*, L. Fang, R. Long, X. Lan*, and K.-C. Chou*, “iEnhancer-2L: a two-layer predictor for identifying enhancers and their strength by pseudo k-tuple nucleotide composition,” Bioinformatics,2016.
3.Z. Chen#, X. Lan#, J. M. Thomas-Ahner, D. Wu, X. Liu, Z. Ye, L. Wang, B. Sunkel, C. Grenade, J.Chen, et al., “Agonist and antagonist switch DNA motifs recognized by human androgen receptor in prostate cancer,” The EMBO Journal, 2015.
4.Z. Chen, X. Lan, D. Wu, B. Sunkel, Z. Ye, J. Huang, Z. Liu, S. K. Clinton, V. X. Jin, and Q. Wang,“Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer,”Nature Communications, vol. 6, 2015.
5.N. E. Banovich#, X. Lan#, G. McVicker, B. Van de Geijn, J. F. Degner, J. D. Blischak, J. Roux, J. K. Pritchard, and Y. Gilad, “Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels,” PLoS Genetics, vol. 10, no. 9, e1004663, 2014.
6.P.-Y. Hsu, H.-K. Hsu, X. Lan, L. Juan, P. S. Yan, J. Labanowska, N. Heerema, T.-H. Hsiao, Y.-C. Chiu, Y. Chen, et al., “Amplification of distant estrogen response elements deregulates target genes associated with tamoxifen resistance in breast cancer,” Cancer Cell, vol. 24, no. 2, pp. 197–212, 2013
7.X. Lan, H. Witt, K. Katsumura, Z. Ye, Q. Wang, E. H. Bresnick, P. J. Farnham, and V. X. Jin,“Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages,” Nucleic Acids Research, vol. 40, no. 16, pp. 7690–7704, 2012.
8.X. Lan, P. J. Farnham, and V. X. Jin, “Uncovering transcription factor modules using one-and three-dimensional analyses,” Journal of Biological Chemistry, vol. 287, no. 37, pp. 30 914–30 921, 2012
9.X. Lan, R. Bonneville, J. Apostolos, W. Wu, and V. X. Jin, “W-ChIPeaks: a comprehensive web application tool for processing ChIP-chip and ChIP-seq data,” Bioinformatics, vol. 27, no. 3, pp. 428–430, 2011.
10.X. Lan, C. Adams, M. Landers, M. Dudas, D. Krissinger, G. Marnellos, R. Bonneville, M. Xu, J.Wang, T. H.-M. Huang, et al., “High resolution detection and analysis of CpG dinucleotides methylation using MBD-Seq technology,” PLoS ONE, vol. 6, no. 7, e22226, 2011.